Patient Zero – Dynamic Zombie Outbreak 1.0
341
11
341
11
Patient Zero - Dynamic Zombie Outbreak [.NET]
One infected civilian. One city. No two outbreaks are the same.
Patient Zero is a dynamic zombie outbreak simulation for GTA V Enhanced. Start with a single infected NPC and watch the outbreak spread naturally through Los Santos as civilians panic, fight back, police respond and the military escalates the situation.
Sometimes the infection is contained quickly.
Sometimes the city completely falls apart.
Installation
Requirements
GTA V Enhanced
Script Hook V
Script Hook V .NET Enhanced 3.9
Installation Guide:
Install Script Hook V.
Install Script Hook V .NET Enhanced.
Place PatientZero.3.cs inside your GTA V scripts folder.
Grand Theft Auto V
-scripts
-PatientZero.3.cs
Launch Story Mode.
Press J to begin.
Controls
J - Start / Pause outbreak
F11 - Toggle cinematic camera
Page Up - Infect nearest healthy NPC
Page Down - Reset the outbreak
Features
Dynamic Infection
Every outbreak begins with Patient Zero.
The infected hunt nearby civilians and spread the virus from person to person. Because NPCs, traffic and locations are constantly changing, the outbreak develops differently every time.
Start the infection anywhere in Los Santos and see what happens.
Escalating Response
The city reacts as the infection grows:
20 Infected - Civilian Resistance
25 Infected - Special Infected Begin Appearing
30 Infected - Police Response
50 Infected - Military Deployment
70 Infected - Tank Response
85 Infected - Air Support / Airstrikes
100 Infected - NOOSE & Heavy Response
What starts as one infected civilian can eventually turn into a full-scale emergency.
Special Infected
As the virus mutates, stronger infected can appear:
Sprinter - Faster and more aggressive
Brute - Stronger and much harder to kill
Screamer - Creates additional chaos during larger outbreaks
Civilian Panic & Traffic Chaos
Civilians may flee, become trapped in traffic, abandon vehicles or fight back.
This creates unpredictable situations where civilians, infected, police and military forces can all collide at once.
Police, NOOSE & Air Support
As the outbreak escalates, increasingly powerful forces attempt to contain it.
Expect police, armed civilians, military soldiers, tanks, NOOSE teams, jets and heavy-response events.
No Two Outbreaks Are the Same
Patient Zero is built around emergent gameplay.
Different people get infected.
Different civilians fight back.
Traffic changes.
Special infected appear in different situations.
Police and military encounters develop differently.
One outbreak may collapse almost immediately.
Another may reach 100 infected and overwhelm the city.
Additional Details
Patient Zero also includes:
Persistent infected
Blood and damage effects
Infection audio cues
Outbreak atmosphere/music
Increased infected aggression
Large-scale NPC battles
Cinematic camera mode
Recommended Way To Play
For the best experience, start small.
Find a busy area, infect one civilian, then watch the situation develop naturally.
The fun is seeing whether Los Santos can contain the outbreak before it becomes unstoppable.
Content Creators
You are welcome to use Patient Zero in YouTube videos, Shorts, streams, TikToks and GTA experiments.
If you create content using the mod, I'd really appreciate it if you could credit Patient Zero and link my YouTube channel in your description:
YouTube:
https://www.youtube.com/@brodiebtw
Feel free to send me your video too - I'd love to see the outbreaks people create.
Feedback
If you encounter bugs or have ideas for future infected types, outbreak events or response mechanics, leave a comment.
Patient Zero is designed to keep evolving.
One infected NPC. An entire city trying to stop it.
Start the infection and see what happens.
One infected civilian. One city. No two outbreaks are the same.
Patient Zero is a dynamic zombie outbreak simulation for GTA V Enhanced. Start with a single infected NPC and watch the outbreak spread naturally through Los Santos as civilians panic, fight back, police respond and the military escalates the situation.
Sometimes the infection is contained quickly.
Sometimes the city completely falls apart.
Installation
Requirements
GTA V Enhanced
Script Hook V
Script Hook V .NET Enhanced 3.9
Installation Guide:
Install Script Hook V.
Install Script Hook V .NET Enhanced.
Place PatientZero.3.cs inside your GTA V scripts folder.
Grand Theft Auto V
-scripts
-PatientZero.3.cs
Launch Story Mode.
Press J to begin.
Controls
J - Start / Pause outbreak
F11 - Toggle cinematic camera
Page Up - Infect nearest healthy NPC
Page Down - Reset the outbreak
Features
Dynamic Infection
Every outbreak begins with Patient Zero.
The infected hunt nearby civilians and spread the virus from person to person. Because NPCs, traffic and locations are constantly changing, the outbreak develops differently every time.
Start the infection anywhere in Los Santos and see what happens.
Escalating Response
The city reacts as the infection grows:
20 Infected - Civilian Resistance
25 Infected - Special Infected Begin Appearing
30 Infected - Police Response
50 Infected - Military Deployment
70 Infected - Tank Response
85 Infected - Air Support / Airstrikes
100 Infected - NOOSE & Heavy Response
What starts as one infected civilian can eventually turn into a full-scale emergency.
Special Infected
As the virus mutates, stronger infected can appear:
Sprinter - Faster and more aggressive
Brute - Stronger and much harder to kill
Screamer - Creates additional chaos during larger outbreaks
Civilian Panic & Traffic Chaos
Civilians may flee, become trapped in traffic, abandon vehicles or fight back.
This creates unpredictable situations where civilians, infected, police and military forces can all collide at once.
Police, NOOSE & Air Support
As the outbreak escalates, increasingly powerful forces attempt to contain it.
Expect police, armed civilians, military soldiers, tanks, NOOSE teams, jets and heavy-response events.
No Two Outbreaks Are the Same
Patient Zero is built around emergent gameplay.
Different people get infected.
Different civilians fight back.
Traffic changes.
Special infected appear in different situations.
Police and military encounters develop differently.
One outbreak may collapse almost immediately.
Another may reach 100 infected and overwhelm the city.
Additional Details
Patient Zero also includes:
Persistent infected
Blood and damage effects
Infection audio cues
Outbreak atmosphere/music
Increased infected aggression
Large-scale NPC battles
Cinematic camera mode
Recommended Way To Play
For the best experience, start small.
Find a busy area, infect one civilian, then watch the situation develop naturally.
The fun is seeing whether Los Santos can contain the outbreak before it becomes unstoppable.
Content Creators
You are welcome to use Patient Zero in YouTube videos, Shorts, streams, TikToks and GTA experiments.
If you create content using the mod, I'd really appreciate it if you could credit Patient Zero and link my YouTube channel in your description:
YouTube:
https://www.youtube.com/@brodiebtw
Feel free to send me your video too - I'd love to see the outbreaks people create.
Feedback
If you encounter bugs or have ideas for future infected types, outbreak events or response mechanics, leave a comment.
Patient Zero is designed to keep evolving.
One infected NPC. An entire city trying to stop it.
Start the infection and see what happens.
First Uploaded: October 10, 2026
Last Updated: October 11, 2026
Last Downloaded: 15 minutes ago
12 Comments
Patient Zero - Dynamic Zombie Outbreak [.NET]
One infected civilian. One city. No two outbreaks are the same.
Patient Zero is a dynamic zombie outbreak simulation for GTA V Enhanced. Start with a single infected NPC and watch the outbreak spread naturally through Los Santos as civilians panic, fight back, police respond and the military escalates the situation.
Sometimes the infection is contained quickly.
Sometimes the city completely falls apart.
Installation
Requirements
GTA V Enhanced
Script Hook V
Script Hook V .NET Enhanced 3.9
Installation Guide:
Install Script Hook V.
Install Script Hook V .NET Enhanced.
Place PatientZero.3.cs inside your GTA V scripts folder.
Grand Theft Auto V
-scripts
-PatientZero.3.cs
Launch Story Mode.
Press J to begin.
Controls
J - Start / Pause outbreak
F11 - Toggle cinematic camera
Page Up - Infect nearest healthy NPC
Page Down - Reset the outbreak
Features
Dynamic Infection
Every outbreak begins with Patient Zero.
The infected hunt nearby civilians and spread the virus from person to person. Because NPCs, traffic and locations are constantly changing, the outbreak develops differently every time.
Start the infection anywhere in Los Santos and see what happens.
Escalating Response
The city reacts as the infection grows:
20 Infected - Civilian Resistance
25 Infected - Special Infected Begin Appearing
30 Infected - Police Response
50 Infected - Military Deployment
70 Infected - Tank Response
85 Infected - Air Support / Airstrikes
100 Infected - NOOSE & Heavy Response
What starts as one infected civilian can eventually turn into a full-scale emergency.
Special Infected
As the virus mutates, stronger infected can appear:
Sprinter - Faster and more aggressive
Brute - Stronger and much harder to kill
Screamer - Creates additional chaos during larger outbreaks
Civilian Panic & Traffic Chaos
Civilians may flee, become trapped in traffic, abandon vehicles or fight back.
This creates unpredictable situations where civilians, infected, police and military forces can all collide at once.
Police, NOOSE & Air Support
As the outbreak escalates, increasingly powerful forces attempt to contain it.
Expect police, armed civilians, military soldiers, tanks, NOOSE teams, jets and heavy-response events.
No Two Outbreaks Are the Same
Patient Zero is built around emergent gameplay.
Different people get infected.
Different civilians fight back.
Traffic changes.
Special infected appear in different situations.
Police and military encounters develop differently.
One outbreak may collapse almost immediately.
Another may reach 100 infected and overwhelm the city.
Additional Details
Patient Zero also includes:
Persistent infected
Blood and damage effects
Infection audio cues
Outbreak atmosphere/music
Increased infected aggression
Large-scale NPC battles
Cinematic camera mode
Recommended Way To Play
For the best experience, start small.
Find a busy area, infect one civilian, then watch the situation develop naturally.
The fun is seeing whether Los Santos can contain the outbreak before it becomes unstoppable.
Content Creators
You are welcome to use Patient Zero in YouTube videos, Shorts, streams, TikToks and GTA experiments.
If you create content using the mod, I'd really appreciate it if you could credit Patient Zero and link my YouTube channel in your description:
YouTube:
https://www.youtube.com/@brodiebtw
Feel free to send me your video too - I'd love to see the outbreaks people create.
Feedback
If you encounter bugs or have ideas for future infected types, outbreak events or response mechanics, leave a comment.
Patient Zero is designed to keep evolving.
One infected NPC. An entire city trying to stop it.
Start the infection and see what happens.
One infected civilian. One city. No two outbreaks are the same.
Patient Zero is a dynamic zombie outbreak simulation for GTA V Enhanced. Start with a single infected NPC and watch the outbreak spread naturally through Los Santos as civilians panic, fight back, police respond and the military escalates the situation.
Sometimes the infection is contained quickly.
Sometimes the city completely falls apart.
Installation
Requirements
GTA V Enhanced
Script Hook V
Script Hook V .NET Enhanced 3.9
Installation Guide:
Install Script Hook V.
Install Script Hook V .NET Enhanced.
Place PatientZero.3.cs inside your GTA V scripts folder.
Grand Theft Auto V
-scripts
-PatientZero.3.cs
Launch Story Mode.
Press J to begin.
Controls
J - Start / Pause outbreak
F11 - Toggle cinematic camera
Page Up - Infect nearest healthy NPC
Page Down - Reset the outbreak
Features
Dynamic Infection
Every outbreak begins with Patient Zero.
The infected hunt nearby civilians and spread the virus from person to person. Because NPCs, traffic and locations are constantly changing, the outbreak develops differently every time.
Start the infection anywhere in Los Santos and see what happens.
Escalating Response
The city reacts as the infection grows:
20 Infected - Civilian Resistance
25 Infected - Special Infected Begin Appearing
30 Infected - Police Response
50 Infected - Military Deployment
70 Infected - Tank Response
85 Infected - Air Support / Airstrikes
100 Infected - NOOSE & Heavy Response
What starts as one infected civilian can eventually turn into a full-scale emergency.
Special Infected
As the virus mutates, stronger infected can appear:
Sprinter - Faster and more aggressive
Brute - Stronger and much harder to kill
Screamer - Creates additional chaos during larger outbreaks
Civilian Panic & Traffic Chaos
Civilians may flee, become trapped in traffic, abandon vehicles or fight back.
This creates unpredictable situations where civilians, infected, police and military forces can all collide at once.
Police, NOOSE & Air Support
As the outbreak escalates, increasingly powerful forces attempt to contain it.
Expect police, armed civilians, military soldiers, tanks, NOOSE teams, jets and heavy-response events.
No Two Outbreaks Are the Same
Patient Zero is built around emergent gameplay.
Different people get infected.
Different civilians fight back.
Traffic changes.
Special infected appear in different situations.
Police and military encounters develop differently.
One outbreak may collapse almost immediately.
Another may reach 100 infected and overwhelm the city.
Additional Details
Patient Zero also includes:
Persistent infected
Blood and damage effects
Infection audio cues
Outbreak atmosphere/music
Increased infected aggression
Large-scale NPC battles
Cinematic camera mode
Recommended Way To Play
For the best experience, start small.
Find a busy area, infect one civilian, then watch the situation develop naturally.
The fun is seeing whether Los Santos can contain the outbreak before it becomes unstoppable.
Content Creators
You are welcome to use Patient Zero in YouTube videos, Shorts, streams, TikToks and GTA experiments.
If you create content using the mod, I'd really appreciate it if you could credit Patient Zero and link my YouTube channel in your description:
YouTube:
https://www.youtube.com/@brodiebtw
Feel free to send me your video too - I'd love to see the outbreaks people create.
Feedback
If you encounter bugs or have ideas for future infected types, outbreak events or response mechanics, leave a comment.
Patient Zero is designed to keep evolving.
One infected NPC. An entire city trying to stop it.
Start the infection and see what happens.
First Uploaded: October 10, 2026
Last Updated: October 11, 2026
Last Downloaded: 15 minutes ago
5mods on Discord
Legacy version?
Hardcore man
@NullVoid Developed for Enhanced sorry
@Starfox1993 I appreciate the feedback!
@brodiebtw Can you make the zombies come after you though instead of them just going around attacking others?
@Starfox1993 The purpose of the mod is to be an AI vs AI simulation, but I'll think about this for an alternate version :)
Can you also infect pads yourself?
@Herobrine7707 Yes use the PageUp key to infect the nearest NPC
@brodiebtw Does the mod need to be activated beforehand?
@Herobrine7707 You can activate the mod with either J or PgUp, however you can speed up the process by repeatedly pressing PgUp to infect the next nearest NPC, hope that helps.
@brodiebtw ok thanks
Diamond men, but please make it for Legacy